The tumor microenvironment contains normal cells, tumor cells, lymphocytes, and blood vessels. The identification and interaction of these tumor microenvironment constituents aids in diagnostics, treatment and response measures.

Immuno-Oncology TargetsCatalog #Clone #Applications
ACTA2A700-082BLR082GWB, IHC, ICC
AHRA700-118BLR118HWB, IP, IHC, ICC
Arginase 1A700-036
BLR036FWB, IP, IHC, ICC, IHC-IF
B7-H3/CD276A700-025
BLR025FWB, IP, IHC, ICC, IHC-IF, F
B7-H3/CD276A700-026
BLR026FWB, IP, IHC, ICC, F
B7-H4A700-043
BLR043FWB, IP, IHC, ICC, IHC-IF
BMI1A700-119BLR119HWB, IP, IHC, ICC
c-MafA700-045BLR045FWB, IP, IHC, ICC
CD3EA700-016
BL-298-5D12WB, IP, IHC, ICC, IHC-IF, F, mIF
CD3ZA700-017
BL-336-1B2WB, IP, IHC, IHC-IF, F
CD4A700-015
BL-155-1C11WB, IP, IHC, mIF
CD8AA700-044
BLR044FWB, IHC, IHC-IF, mIF
CD8 alpha [C8/144B]A500-021A
C8/144BIHC, IHC-IF, F
CD11bA700-107BLR107HWB, IP, IHC, ICC
CD20 [L26]A500-017A
L26WB, IHC, IHC-IF, F, mIF
CD27A700-083
BLR083GWB, IP, IHC, ICC
CD30A700-055
BLR055FWB, IP, IHC, ICC, IHC-IF
CD33A700-061
BLR061GWB, IP, IHC
CD38A700-123BLR123HWB, IP, IHC, ICC
CD40A700-056
BLR056FWB, IP, IHC, ICC, IHC-IF
CD44A700-038
BLR038FWB, IP, IHC, ICC, F
CD45A700-012
BL-178-12C7WB, IP, IHC, ICC, IHC-IF, F
CD45RO [UCHL-1]A500-020A
UCHL-1WB, IHC, ICC, IHC-IF, mIF
CD68 [KP-1]A500-018A
KP-1IHC, IHC-IF, F, mIF
CD73A700-054
BLR054FWB, IHC, ICC, IHC-IF
CD74A500-023ALN2WB, IHC, ICC
CD86A700-029
BLR029FWB, IP, ICC
CD86A700-030
BLR030FWB, IP, IHC, ICC
CD96A700-065
BLR065GWB, IP, IHC, ICC
CD112A700-071
BLR071GWB, IHC, ICC, IHC-IF
CD133A700-093BLR093GWB, IHC, ICC
CD137A700-051
BLR051FWB, IP, IHC, ICC
CD155A700-074
BLR074GWB, IHC, ICC
CD163A700-087
BLR087GIHC
CD206/Mannose ReceptorA700-109BLR109HWB, IP, IHC, ICC
CEACAM1A700-090BLR090GWB, IP, IHC, ICC
CEACAM8/CD66bA700-111BLR111HWB, IP, IHC
CK [AE1/AE3]A500-019A
AE1/AE3IHC, IHC-IF, ICC-IF, mIF
Cytokeratin 20A700-105BLR105HWB, IP, IHC, ICC
DNAM-1/CD226A700-063BLR063GWB, IP, IHC, ICC
EOMESA700-104BLR104HWB, IP, IHC, ICC
FOXP3A700-034
BLR034FWB, IP, IHC, ICC, IHC-IF, mIF
GATA3A700-121BLR121HWB, IP, IHC, ICC
GITR/TNFRSF18A700-068
BLR068GWB, IP, IHC, ICC, IHC-IF
GP130/CD130A700-114BLR114HWB, ICC
Granzyme BA700-022
BLR022EWB, IHC, ICC, IHC-IF, mIF
hIgG4A700-113BLR113HWB, IHC
HLA-DR [LN3]A500-022A
LN3WB, IHC, ICC, IHC-IF
HVEMA700-062
BLR062GWB, IHC, ICC
IDO1A700-031BLR031FWB, IHC, ICC, IHC-IF
IDO1A700-040
BLR040FWB, IP
IRF1A700-039
BLR039FWB, IP, IHC, ICC, F
Ki-67A700-021
BLR021EWB, IHC, ICC, IHC-IF, ICC-IF, F, mIF
LAG3A700-027
BLR027FWB, IP, IHC, ICC, IHC-IF, mIF
LAG3A700-028
BLR028FWB, IP, IHC, ICC, IHC-IF
N-CadherinA700-097BLR097GWB, IP, ICC
OX40/CD134A700-042
BLR042FWB, IP, IHC, ICC, IHC-IF
PBRM1A700-019BL-39-2C3WB, IP, IHC, ICC, IHC-IF
PCNAA500-024APC10WB, IP, IHC, ICC
PCNAA700-075
BLR075GWB, IHC, ICC
PD-1A700-076
BLR076GIHC
PD-L1A700-020
BLR020EWB, IP, IHC, IHC-IF, ICC-IF, mIF
RUNX3A700-122BLR122HWB, IP, IHC, ICC
SOX10A700-080
BLR080GWB, IP, IHC, ICC, mIF
STAT1A700-125BLR125HWB, IP
STAT3A700-098BLR098GWB, IP, IHC, ICC
STAT5AA700-124BLR124HWB, IP, IHC, ICC
T-bet/TBX21A700-110BLR110HWB, IP, IHC, ICC
TIGITA700-047
BLR047FWB, IHC, IHC-IF
TIM3A700-033
BLR033FWB, IHC, ICC, IHC-IF
VE-CadherinA700-091BLR091GWB, IP, IHC, ICC
VimentinA700-100BLR100GWB, IHC, ICC
VISTAA700-035
BLR035FWB, IP, IHC, ICC, IHC-IF

Detection of human CD8 (red) and FoxP3 (green) in FFPE colon carcinoma. Rabbit anti-CD8a recombinant monoclonal [BLR044F] (A700-044) and rabbit anti-FoxP3 recombinant monoclonal [BLR034F] (A700-034). Secondary: HRP-conjugated goat-anti-rabbit IgG (A120-501P) Substrate: Opal™ 590 and 520. Counterstain: DAPI (blue).

Detection of human CD3 (green), CD20 (magenta), CD68 (yellow), and Cytokeratin (red) in FFPE human NSCLC. Antibodies: Rabbit anti-CD3E recombinant monoclonal [BL-298-5D12] (A700-016), mouse anti-CD20 monoclonal [L26] (A500-017A), mouse anti-CD68 recombinant monoclonal [KP-1] (A500-018A), mouse anti-Cytokeratin monoclonal [AE1/AE3] (A500-019A). Substrate: Opal™ reagent. Counterstain: DAPI (blue).

 

Detection of human VISTA (orange) in FFPE human tonsil. Antibody: Rabbit anti-VISTA recombinant monoclonal [BLR035F] (A700-035). Secondary: HRP-conjugated goat-anti-rabbit IgG (A120-501P). Substrate: Opal™ 620. Counterstain: DAPI (blue).

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